Genetics

This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease.  

MuscleGenes has been chosen to partner with leading sports science researchers at Loughborough University on the FTO gene. This research will further our understanding of the fundamental question, "Am I genetically programmed to be overweight?"  

Gene therapy or stem cell therapy for ataxia #Neurology #Genetics  

Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT...  

Whole genome sequencing (WGS) of pathogens enables the sources and patterns of transmission to be identified during specific disease outbreaks and promises to transform epidemiological research on communicable diseases. This review discusses new insights into disease spread and transmission that have come from the use of WGS, particularly when combined with genomic scale phylogenetic analyses. These include elucidation of the mechanisms of cross species transmission, the potential modes of pathogen transmission, and which people in the population contribute most to transmission. Particular attention is paid to the ability of WGS to resolve individual patient to patient transmission events. Importantly, WGS data seem to be sufficiently discriminatory to target cases linked to community or hospital contacts and hence prevent further spread, and to investigate genetically related cases without a clear epidemiological link. Approaches to combine evidence from epidemiological with genomic sequencing observations are summarised. Ongoing genomic surveillance can identify determinants of transmission, monitor pathogen evolution and adaptation, ensure the accurate and timely diagnosis of infections with epidemic potential, and refine strategies for their control.  

Whole genome sequencing (WGS) of pathogens enables the sources and patterns of transmission to be identified during specific disease outbreaks and promises to transform epidemiological research on communicable diseases. This review discusses new insights into disease spread and transmission that have come from the use of WGS, particularly when combined with genomic scale phylogenetic analyses. These include elucidation of the mechanisms of cross species transmission, the potential modes of pathogen transmission, and which people in the population contribute most to transmission. Particular attention is paid to the ability of WGS to resolve individual patient to patient transmission events. Importantly, WGS data seem to be sufficiently discriminatory to target cases linked to community or hospital contacts and hence prevent further spread, and to investigate genetically related cases without a clear epidemiological link. Approaches to combine evidence from epidemiological with genomic sequencing observations are summarised. Ongoing genomic surveillance can identify determinants of transmission, monitor pathogen evolution and adaptation, ensure the accurate and timely diagnosis of infections with epidemic potential, and refine strategies for their control.  

Classifications of antibiotics - a useful summary. The Table is no way complete. Kindly Ignore Spelling mistakes Checkout mynotes4usmle.tumblr.com for more  

- Fanconi (“Fan-of-cones”) syndrome: reabsorptive defects in the proximal convoluted tubule - Bartter (“Bart”) syndrome: reabsorptive defect in thick ascending loop of Henele - Gitelman (“Giggle-man”) syndrome: reabsorptive defect of NaCl in distal convoluted tubule - Liddle (“Chicken Little”) syndrome: increased sodium reabsorption in the collecting tubules  

The TDWI/Hatch team had good fortune to attend the amazing Personalized Medicine World Conference put on by Tal and Gadi Behar at the Computer History Museum...  

Pat Salber (@docweighsin) chats with Oracle's Jonathan Sheldon (Global VP for Health Care) about meeting the data demands of Precision Medicine. He says that...  

Pat Salber (@docweighsin) chats with Oracle's Jonathan Sheldon (Global VP for Health Care) about meeting the data demands of Precision Medicine. He says that...  

Stream Radiation for brain metastases, and the genetics of ischaemic stroke by BMJ talk medicine from desktop or your mobile device  

Implicated as a substantial factor behind the association in genetics study.  

Short people may be more likely to have heart disease, and that increased risk could be linked to the genetics that also determine height, a British-led research team suggests.  

Genetic factors appear to significantly increase the risk for sudden cardiac death among patients receiving dialysis.  

In half of all cancer patients, tumor-only gene sequencing is not enough to guide therapeutic decisions on the use of precision cancer agents.  

: A new analysis of primary and second prevention studies shows that a genetic risk profile helps identify those at risk for coronary heart disease and those who would benefit from statins.  

Myriad RBM, a wholly owned subsidiary of Myriad Genetics, Inc. has announced that it will assist the Institut Pasteur in a public-private research collaboration to fight the global...  

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel...  

Myriad Genetics, Inc. has announced that results from the EMPATHY-P clinical study of Prolaris in patients newly diagnosed with prostate cancer will be highlighted at the 30th Annual Congress...